For my teeth at least (and about half of the reviewers online), it takes multiple 3d picks to floss each time due to breaking. It is rare to have a Plackers Glide pick break, but have had them stretch if the floss gets a little sideways and gets a little bit stuck between teeth. Regular Plackers aren't PTFE like both Glides are, just a regular piece of floss that rarely shreds or breaks. Also, the pick part of Plackers are considerably more substantial than the flimsy Oral-B.
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