I was able to get it to work on Mac with the "PC key" from Amazon with the GOTY edition. You need to have a Steam account to do so but once you order the game, go to your account and copy the key for the game. Then open Steam on your Mac and go under "Games" -> "Activate a Product on Steam...", hit next and agree to stuff, then copy the key, then it should activate, then download the game. I was able to get it to run and all of the DLC content is in the game (Civ IV had DLC separate on Steam for me so I thought I would put it out there).
Last edited by krolarthur; 08-24-2012 at 08:15 AM..
Reason: More detail.