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60-Count Chapter One Immunity Gummies (Elderberry, Zinc & Vitamin C) EXPIRED

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Apex Nutrition via Amazon has 60-Count Chapter One Immunity Gummies (Elderberry, Zinc & Vitamin C) on sale prices for $6.27 when you apply promo code IMMUGUM50 at checkout via Subscribe & Save. Shipping is free with Prime or on orders $25+. Thanks iconian
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$6.27 or less @ Amazon when you checkout via s&s and use promo code IMMUGUM50
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30 Comments

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Joined Nov 2013
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#16
Quote from texst
:
Well, for one, you shouldn't take "Vitamin B Complex" b/c it has inactive, neurotoxic B6 (pyridoxine) instead of active P5P.

https://pubmed.ncbi.nlm.nih.gov/28716455/
Pyridoxine induced cell death in a concentration-dependent way in SHSY5Y cells. ... the present study indicates that the neuropathy observed after taking a relatively high dose of vitamin B6 supplements is due to pyridoxine. The inactive form pyridoxine competitively inhibits the active pyridoxal-5'-phosphate. Consequently, symptoms of vitamin B6 supplementation are similar to those of vitamin B6 deficiency.
Is B12 okay?
I currently take B12 gel capsules daily
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#17
Quote from texst
:
Well, for one, you shouldn't take "Vitamin B Complex" b/c it has inactive, neurotoxic B6 (pyridoxine) instead of active P5P.

https://pubmed.ncbi.nlm.nih.gov/28716455/
Pyridoxine induced cell death in a concentration-dependent way in SHSY5Y cells. ... the present study indicates that the neuropathy observed after taking a relatively high dose of vitamin B6 supplements is due to pyridoxine. The inactive form pyridoxine competitively inhibits the active pyridoxal-5'-phosphate. Consequently, symptoms of vitamin B6 supplementation are similar to those of vitamin B6 deficiency.
'All cases of vitamin B6 toxicity are from supratherapeutic dosing..'

Or just don't take a ridiculous amount.
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#18
Thanks! Sadly winter is coming and even though stuff like this does nothing, it tastes good!!
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#19
It's saying code is expired :/
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#20
Quote from slyevo
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It's saying code is expired :/
Yep, saved me the trouble of figuring out if these are worthless or not.


THERE WAS A PROBLEM
The promotional code you entered is not valid.
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#21
I must be demented, our account is an amazon business account, and I can't seem to find a place to enter the promo code anywhere.
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Our community has rated this post as helpful. If you agree, why not thank ?
#22
Quote from texst
:
Well, for one, you shouldn't take "Vitamin B Complex" b/c it has inactive, neurotoxic B6 (pyridoxine) instead of active P5P.

https://pubmed.ncbi.nlm.nih.gov/28716455/
Pyridoxine induced cell death in a concentration-dependent way in SHSY5Y cells. ... the present study indicates that the neuropathy observed after taking a relatively high dose of vitamin B6 supplements is due to pyridoxine. The inactive form pyridoxine competitively inhibits the active pyridoxal-5'-phosphate. Consequently, symptoms of vitamin B6 supplementation are similar to those of vitamin B6 deficiency.
you're talking about very high/prolonged dose of pyridoxine. but yes, it is ideal to take coenzymated forms of B (methylcobalamin, P5P, methyl folate, etc). and you can certainly find coenzymated forms.

but this whole nutritional mechanism/interrelationships apply not only to B6, but for practically all (every single vitamin and minerals are intertwined in this synergistic/antagonistic relationship). e.g. supplementing single isomer of vitamin E can also be counterproductive (cause imbalance--there are 8 isomers and of them, gamma tocotrienol/tocopherols are the most important). too much vitamin D enhances calcium absorption (that can cause arterial calcification) and can decrease magnesium and potassium levels. excess vitamin A can cause calcium loss. high calcium can depress zinc absorption. zinc and vitamin C can interfere with copper metabolism, B1 can be antagonistic to B12. vitamin C can enhance iron absorption that can indirectly lead to B12 deficiency. the list goes on.

i thought 240Vic's advice was relatively sound. s/he is not going to write a novel about the best forms and ratios. and s/he made a good point about how companies tend to sugarcoat the ingredient with just juice for flavoring/coloring instead of using extracts/active forms of elderberry.
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Last edited by MrsFrizzleGaveMeLSD September 15, 2020 at 05:50 PM.

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#23
Quote from MrsFrizzleGaveMeLSD
:
you're talking about very high/prolonged dose of pyridoxine. but yes, it is ideal to take coenzymated forms of B (methylcobalamin, P5P, methyl folate, etc). and you can certainly find coenzymated forms.

but this whole nutritional mechanism/interrelationships apply not only to B6, but for practically all (every single vitamin and minerals are intertwined in this synergistic/antagonistic relationship). e.g. supplementing single isomer of vitamin E can also be counterproductive (cause imbalance--there are 8 isomers and of them, gamma tocotrienol/tocopherols are the most important). too much vitamin D enhances calcium absorption (that can cause arterial calcification) and can decrease magnesium and potassium levels. excess vitamin A can cause calcium loss. high calcium can depress zinc absorption. zinc and vitamin C can interfere with copper metabolism, B1 can be antagonistic to B12. vitamin C can enhance iron absorption that can indirectly lead to B12 deficiency. the list goes on.

i thought 240Vic's advice was relatively sound. s/he is not going to write a novel about the best forms and ratios. and s/he made a good point about how companies tend to sugarcoat the ingredient with just juice for flavoring/coloring instead of using extracts/active forms of elderberry.
I like your posts. Please post more
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#24
Quote from slacky
:
Yep, saved me the trouble of figuring out if these are worthless or not.


THERE WAS A PROBLEM
The promotional code you entered is not valid.
Same for me as well
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#25
Quote from MrsFrizzleGaveMeLSD
:
you're talking about very high/prolonged dose of pyridoxine. but yes, it is ideal to take coenzymated forms of B (methylcobalamin, P5P, methyl folate, etc). and you can certainly find coenzymated forms.

but this whole nutritional mechanism/interrelationships apply not only to B6, but for practically all (every single vitamin and minerals are intertwined in this synergistic/antagonistic relationship). e.g. supplementing single isomer of vitamin E can also be counterproductive (cause imbalance--there are 8 isomers and of them, gamma tocotrienol/tocopherols are the most important). too much vitamin D enhances calcium absorption (that can cause arterial calcification) and can decrease magnesium and potassium levels. excess vitamin A can cause calcium loss. high calcium can depress zinc absorption. zinc and vitamin C can interfere with copper metabolism, B1 can be antagonistic to B12. vitamin C can enhance iron absorption that can indirectly lead to B12 deficiency. the list goes on.

i thought 240Vic's advice was relatively sound. s/he is not going to write a novel about the best forms and ratios. and s/he made a good point about how companies tend to sugarcoat the ingredient with just juice for flavoring/coloring instead of using extracts/active forms of elderberry.
Well agree with your sentiments you are woefully mistaken on your synergy combinations! Vitamin D needs Boron, Vitamin A, K2 & other cofactor nutrients for proper calcium metabolism & utilization into bones! Also it's copper that is typically said to compete with zinc for absorption though I believe I recently read calcium is in that competition too. The point, in accord with the WAFP philosophy, is that, if needed, whole food supplements (like cod liver oil, butter oil, unfortified nutritional yeast, etc) ought to be consumed rather than synthetic/fractionated/isolated vitamins to prevent the voiding of nature's synergy!
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#26
Quote from 240Vic
:
I formulate vitamins for a living. If you see Elder Berries in chewables, it's for flavoring and coloring. Stick to syrup or if you really want the benefits look for Elder Berry Extract in the label claim. Consume Vitamin C, Vitamin B complex, and Zinc in proper dosages to maximize the fight against flu like symptoms and boost immunity defense.
the deal is dead. But just for my knowledge these are no good you saying as they belong to the elderberry for flavoring and coloring category ?
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#27
Quote from ranibane0309
:
the deal is dead. But just for my knowledge these are no good you saying as they belong to the elderberry for flavoring and coloring category ?
These are good for your vitamin C and Zinc source but adding elder berry to the name is mostly marketing seeing as though studies demonstrate elder berry benefits. Even as a formulator I cannot have final say but the marketing team can, they can say its elderberry even if it's only 0.00001% of 1 serving so long as it's shown on the label claim.
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#28
Quote from orangemetal84
:
Well agree with your sentiments you are woefully mistaken on your synergy combinations! Vitamin D needs Boron, Vitamin A, K2 & other cofactor nutrients for proper calcium metabolism & utilization into bones! Also it's copper that is typically said to compete with zinc for absorption though I believe I recently read calcium is in that competition too. The point, in accord with the WAFP philosophy, is that, if needed, whole food supplements (like cod liver oil, butter oil, unfortified nutritional yeast, etc) ought to be consumed rather than synthetic/fractionated/isolated vitamins to prevent the voiding of nature's synergy!
That's an interesting point you make. I agree with you 100% in terms of naturally getting your vitamins from fruits, meats, and vegetables, but issues arise when you get older and your body does not absorp them as easily as well as those out there that have a natural vitamin deficiency. The raw forms of Vitamin K, Vitamin C, etc are usually incased (suspended) by either silicon dioxide ,HPMC, MCC, etc. so they don't react as one would think. Then they are suspended even more by using dicalcium phosphate or more mcc which have a high compressablility which in turn help make a good tablet and/or capsule. The calcium you see in vitamins and/or medications isn't for bone health but used as a binder. We use "excipients" which you find in most everything you consume to help with lubrication, compression, anticaking, and disintegration. This helps when its manufactured, coated, packaged, and shipped. Its to prevent the said vitamin from decaying while sitting on the shelf or being digested in your body. Also one small note, going deep into the chemistry, zinc is used as an inhibitor therefore making it great defense against the flu which tries to latch onto healthy cells.
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#29
Quote from 240Vic
:
These are good for your vitamin C and Zinc source but adding elder berry to the name is mostly marketing seeing as though studies demonstrate elder berry benefits. Even as a formulator I cannot have final say but the marketing team can, they can say its elderberry even if it's only 0.00001% of 1 serving so long as it's shown on the label claim.
Thank. So how can we tell which one has real elderberry extract and which one is just marketing ?
According to your earlier post this one doesn't claim to have elder berry extract right?
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#30
Quote from ranibane0309
:
Thank. So how can we tell which one has real elderberry extract and which one is just marketing ?
According to your earlier post this one doesn't claim to have elder berry extract right?
It usually says on the label claim. It will say extract. This one has 50mg elderberry but that could be total elderberry mix meaning elderberry plus skin, stems, lubricant and filler. Extracts are usually the pure source meaning the actual vitamin benefit without fillers, hence its more expensive.
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