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240-Count Puritans Pride 3mg Melatonin Supplement Expired
$2.30
$4.99
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Amazon has 240-Count Puritans Pride 3mg Melatonin Supplement on sale for $2.44 - 5% Subscribe & Save = $2.32. Shipping is free while Subscribe & Save is available. Thanks busybugsy
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You may save an additional 15% off on this month's Subscribe & Save items when you subscribe to 5 or more items during your current subscription month. - Discombobulated
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Edited December 3, 2019
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Puritans Pride Melatonin 3 mg Tablets, 240 Count https://www.amazon.com/dp/B004R65...5DbQ3
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View All| Rating: | (4.5 out of 5 stars) |
| Reviews: | 55 Amazon Reviews |
| Product Name: | Puritans Pride Melatonin 3 mg Tablets, 240 Count |
| Product Description: | We are the manufacturer and the only authorized seller of this product. This product has been made with the highest quality ingredients available. Over 40 years in business and 19 million customers served. |
| Manufacturer: | Puritan's Pride |
| Product SKU: | B004R65Q1Q |
| UPC: | 074312179044 |
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Source: UpToDate
https://www.uptodate.co
For me, the sweet spot seems to be 600mcg
Sources:
http://doi.org/10.17925/USN.2014.10.02.
A very small dose (0.3 mg) of melatonin is usually sufficient to restore nighttime plasma melatonin levels to those characteristic of young people, and to accelerate the resumption of sleep after premature awakenings. The much larger doses that are marketed can produce side effects that are not observed when the melatonin in the plasma derives solely from its secretion by the pineal.
https://academic.oup.co
The physiologic melatonin dose (0.3 mg) restored sleep efficiency (P < 0.0001), acting principally in the midthird of the night; it also elevated plasma melatonin levels (P < 0.0008) to normal. The pharmacologic dose (3.0 mg), like the lowest dose (0.1 mg), also improved sleep; however, it induced hypothermia and caused plasma melatonin to remain elevated into the daylight hours. Although control subjects, like insomniacs, had low melatonin levels, their sleep was unaffected by any melatonin dose.
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For me, the sweet spot seems to be 600mcg
Sources:
http://doi.org/10.17925/USN.2014.10.02.
A very small dose (0.3 mg) of melatonin is usually sufficient to restore nighttime plasma melatonin levels to those characteristic of young people, and to accelerate the resumption of sleep after premature awakenings. The much larger doses that are marketed can produce side effects that are not observed when the melatonin in the plasma derives solely from its secretion by the pineal.
https://academic.oup.co
The physiologic melatonin dose (0.3 mg) restored sleep efficiency (P < 0.0001), acting principally in the midthird of the night; it also elevated plasma melatonin levels (P < 0.0008) to normal. The pharmacologic dose (3.0 mg), like the lowest dose (0.1 mg), also improved sleep; however, it induced hypothermia and caused plasma melatonin to remain elevated into the daylight hours. Although control subjects, like insomniacs, had low melatonin levels, their sleep was unaffected by any melatonin dose.
For me, the sweet spot seems to be 600mcg.
Source?
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