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Huge debate on this . My dogs been grain free and healthy since birth. Love signature grain free. If you want to make sure your dog and yourself are getting the best of the best ingredients, make your own food and only use organic non dairy grain free foods.
To my knowledge it is breed specific for the most part
We had 2/3 of our Goldens on grain free and their Taurine was under 200. We changed their diets and it's up to where it should be for them (240-280.)
We have to do bi-yearly blood tests, and a yearly Ultrasound on their chest.
We started this process 2-3 years back, and go for our final this December. So far we are in the "good" and show no issues at all.