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expiredphoinix | Staff posted Nov 27, 2025 12:15 PM
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expiredphoinix | Staff posted Nov 27, 2025 12:15 PM

48-Ct GoodSense Nighttime Sleep-Aid Ultra Tablets (25mg Doxylamine Succinate)

w/ Subscribe & Save

$2.70

$10

73% off
Amazon
34 Comments 7,949 Views
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Deal Details
Amazon has 48-Count GoodSense Nighttime Sleep-Aid Ultra Tablets (25mg Doxylamine Succinate) for $3.58 - 20% when you 'clip' the coupon on product page - 5% when you check out via Subscribe & Save = $2.68. Shipping is free with Prime or on $35+ orders.

Thanks to Deal Hunter phoinix for sharing this deal.

Note: You must be logged into your account. Coupons are typically one use per account. You have the flexibility to manage your Subscribe & Save subscription at any time after your order ships. View Subscribe & Save filler items and our current Subscribe & Save Frontpage deals to unlock up to an extra 15% savings when you have 5 or more items in your current monthly subscription.

Product Details:
  • The active ingredient in GoodSense Nighttime Sleep-Aid Ultra Tablets is doxylamine succinate 25 mg, a nighttime sleep-aid.
  • Don't toss and turn in the middle of the night; GoodSense Nighttime Sleep-Aid Ultra Tablets help you fall asleep so you wake up feeling rejuvenated.
  • To help reduce difficulty in falling asleep.
  • This is for adults and children 12 years of age and over.
  • These sleep-aid pills do not contain gluten.

Editor's Notes

Written by ValPal2011 | Staff

Original Post

Written by phoinix | Staff
Community Notes
About the Poster
Deal Details
Community Notes
About the Poster
Amazon has 48-Count GoodSense Nighttime Sleep-Aid Ultra Tablets (25mg Doxylamine Succinate) for $3.58 - 20% when you 'clip' the coupon on product page - 5% when you check out via Subscribe & Save = $2.68. Shipping is free with Prime or on $35+ orders.

Thanks to Deal Hunter phoinix for sharing this deal.

Note: You must be logged into your account. Coupons are typically one use per account. You have the flexibility to manage your Subscribe & Save subscription at any time after your order ships. View Subscribe & Save filler items and our current Subscribe & Save Frontpage deals to unlock up to an extra 15% savings when you have 5 or more items in your current monthly subscription.

Product Details:
  • The active ingredient in GoodSense Nighttime Sleep-Aid Ultra Tablets is doxylamine succinate 25 mg, a nighttime sleep-aid.
  • Don't toss and turn in the middle of the night; GoodSense Nighttime Sleep-Aid Ultra Tablets help you fall asleep so you wake up feeling rejuvenated.
  • To help reduce difficulty in falling asleep.
  • This is for adults and children 12 years of age and over.
  • These sleep-aid pills do not contain gluten.

Editor's Notes

Written by ValPal2011 | Staff

Original Post

Written by phoinix | Staff

Community Voting

Deal Score
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Price Intelligence

Model: GoodSense Nighttime Sleep-Aid Ultra Tablets, Doxylamine Succinate 25 mg, 48 Count

Deal History 

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Sort: Lowest to Highest | Last Updated 1/11/2026, 12:39 PM
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Top Comments

np1050
3156 Posts
374 Reputation
Pharmacist here. This medication is highly anticholinergic and sedating. Avoid where possible and definitely avoid for regular use. Melatonin, trazodone, or low dose mirtazapine would be safer
tFowl
458 Posts
86 Reputation
Stop using Benadryl regularly for sleep, long term use of Benadryl is linked with dementia
lauralc9
32 Posts
34 Reputation
Yes, MUCH better quality sleep with this than diphenhydramine. I take a half tab nightly and it helps me stay asleep / fall back asleep if I wake up after 3-4 hours.

33 Comments

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Pro
Nov 27, 2025 12:25 PM
3,837 Posts
Joined Oct 2013
freshsqueezed
Pro
Nov 27, 2025 12:25 PM
3,837 Posts
Has anyone tried this and thought it worked better than Benadryl for sleep?
Nov 27, 2025 12:39 PM
10,978 Posts
Joined Jun 2004
rly723Nov 27, 2025 12:39 PM
10,978 Posts
I use 5mg melatonin i want to be knocked out, i get mixed results
Nov 27, 2025 04:45 PM
32 Posts
Joined Jul 2007
lauralc9Nov 27, 2025 04:45 PM
32 Posts
Quote from freshsqueezed :
Has anyone tried this and thought it worked better than Benadryl for sleep?
Yes, MUCH better quality sleep with this than diphenhydramine. I take a half tab nightly and it helps me stay asleep / fall back asleep if I wake up after 3-4 hours.
Nov 27, 2025 05:33 PM
227 Posts
Joined Feb 2020
Enzo954Nov 27, 2025 05:33 PM
227 Posts

Our community has rated this post as helpful. If you agree, why not thank Enzo954

I've been taking Doxylamine Succinate for years. I only taking a 1/4 of a pill at a time now because it knocks you out and it can be hard to wake up in the morning. Take too much and you'll be like a zombie the next day.
2
Nov 27, 2025 06:20 PM
580 Posts
Joined Oct 2015
ksdog317Nov 27, 2025 06:20 PM
580 Posts
Is this a better alternative than lorazepam?
3
Nov 30, 2025 03:55 AM
77 Posts
Joined Jul 2018
SteveA3128Nov 30, 2025 03:55 AM
77 Posts
Quote from freshsqueezed :
Has anyone tried this and thought it worked better than Benadryl for sleep?
To each his own - Both work as H1 blockers so similar in how they work This one tends to last longer (basically double "half-life") so can definitely be more "foggy" in the morning - I'd start low like others mention (1/4 or 1/2 tab) to assess tolerance
1
Nov 30, 2025 10:45 AM
738 Posts
Joined May 2007
Miami305Nov 30, 2025 10:45 AM
738 Posts
https://www.womenshealthmag.com/h...ntia-risk/

Doxylamine succinate is not good for your brain.

CBT - I is the answer.
1

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Nov 30, 2025 10:45 AM
1,096 Posts
Joined Dec 2012
bansh77Nov 30, 2025 10:45 AM
1,096 Posts
Quote from ksdog317 :
Is this a better alternative than lorazepam?
Those won't relax you like a tranquilizer. Ativan used to make me feel like I was well rested even before sleeping. Doxy just sucks the life out of me long after waking.
Nov 30, 2025 11:44 AM
1,938 Posts
Joined Sep 2018

This comment has been rated as unhelpful by Slickdeals users.

Nov 30, 2025 11:55 AM
4,533 Posts
Joined Nov 2013
luckydog97Nov 30, 2025 11:55 AM
4,533 Posts
Quote from bansh77 :
Those won't relax you like a tranquilizer. Ativan used to make me feel like I was well rested even before sleeping. Doxy just sucks the life out of me long after waking.
Ativan is great at reducing anxiety and improving sleep, but having used it myself it shouldn't be taken often. Frequent use and higher doses diminishes the effect, and any development of dependence will result in withdrawal that will heighten the symptoms people are trying to escape (anxiety, insomnia, etc).

Powerful drug to be used with caution. It should be used as medicine, NOT a lifestyle.
1
Nov 30, 2025 12:36 PM
3,156 Posts
Joined Jun 2016
np1050Nov 30, 2025 12:36 PM
3,156 Posts

Our community has rated this post as helpful. If you agree, why not thank np1050

Pharmacist here. This medication is highly anticholinergic and sedating. Avoid where possible and definitely avoid for regular use. Melatonin, trazodone, or low dose mirtazapine would be safer
6
Nov 30, 2025 12:59 PM
3,156 Posts
Joined Jun 2016
np1050Nov 30, 2025 12:59 PM
3,156 Posts
Quote from Enzo954 :
I've been taking Doxylamine Succinate for years. I only taking a 1/4 of a pill at a time now because it knocks you out and it can be hard to wake up in the morning. Take too much and you'll be like a zombie the next day.
Might want to rethink that strategy. The risks with this medication and diphenhydramine are very well established
Nov 30, 2025 01:37 PM
458 Posts
Joined Nov 2007
tFowlNov 30, 2025 01:37 PM
458 Posts

Our community has rated this post as helpful. If you agree, why not thank tFowl

Quote from freshsqueezed :
Has anyone tried this and thought it worked better than Benadryl for sleep?
Stop using Benadryl regularly for sleep, long term use of Benadryl is linked with dementia
1
Nov 30, 2025 01:41 PM
57 Posts
Joined Aug 2009
MrCrumblesNov 30, 2025 01:41 PM
57 Posts
Yes, the research is clear that this can increase your risk of dementia, particularly with regular use. That said, I've only ever used these occasionally, rarely more than half a pill, these days 1/4 a pill. If you're taking a whole pill every (other) night then I would strongly recommend considering another solution.

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Nov 30, 2025 01:46 PM
1,898 Posts
Joined Nov 2009
JRJRNov 30, 2025 01:46 PM
1,898 Posts
Quote from tFowl :
Stop using Benadryl regularly for sleep, long term use of Benadryl is linked with dementia
Hmmmm.. my wife would take a Benadryl or generic version of it every night for sleep aid. She died of a brain tumor three years ago. I wonder if that was a cause or at least a contribution to the glioblastoma?
1

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