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Amazon has select Colgate Optic Toothpaste on sale as listed below when you 'clip' the respective coupon found on the product page and check out via Subscribe & Save. Shipping is free with Prime or on $35+ orders.
Note: You must be logged in to clip coupons; coupons are typically for one-time use. Manage your Subscribe & Save subscription anytime after your order ships. View filler items or Frontpage deals to unlock up to 15% savings with 5+ monthly items.
Thanks to Deal Hunter phoinix for sharing this deal.
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Model: Colgate Optic White with Charcoal Teeth Whitening Toothpaste, Cool Mint, 4.2 Ounce (Pack of 2)
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Quote
from Huffdawg
:
I'll never use a Fluoride toothpaste again after digging into the research more.
Hopefully for the sake of your dental hygiene you get fluoride from other sources. If you're somewhere with it added to your water or a high level of it naturally occurring, you might be fine to avoid toothpaste with fluoride. In those cases, you might, however, want to use toothpaste with arginine instead. Or, you can do topical fluoride treatments and avoid it in toothpaste.
There's considerable evidence of the benefits of fluoride in preventing tooth caries, and not just in children. For example:
Castelo, R., Attik, N., Catirse, A. et al. Is there a preferable management for root caries in middle-aged and older adults? A systematic review. Br Dent J (2021). https://doi.org/10.1038/s41415-021-3003-2
But, if you have peer-reviewed research that shows findings you're concerned about, please provide the references.
Neurodetrimental effects: https://ehjournal.biomedcentral.c...hatgpt.com and https://jamanetwork.com/journals/...hatgpt.com. Dental and skeletal fluorosis for folks that apply toothpaste liberally. Most folks don't understand the "pea sized" amounts. https://www.frontiersin.org/journ...hatgpt.com and wikipedia references several more credible sources. Harvard is doing meta analysis on developmental neurotoxicity risks, especially in children. Lot of studies are starting to come out on mouthwash too. Give it 10 years. I take chewable oral prebiotics that include lactobacillus reuteri and my oral hygiene is better than it's ever been. Fluoride is absolutely great for teeth, no questions there. It's everywhere else that concerns me.
The first article shows: "Neurotoxicity appeared to be dose-dependent, and tentative benchmark dose calculations suggest that safe exposures are likely to be below currently accepted or recommended fluoride concentrations in drinking water." It's thus more about drinking water than the small amounts of fluoride in toothpaste. Let's go from there though.
Infants and children (under the age of 6) would likely have to be swallowing a minimum of 5X the normal amount of daily toothpaste for years to have any possible cognitive detriments. Even then, the cognitive harm might be 1-2 IQ points, which difference has no real-world implications. Very few children >6 or adults are swallowing any toothpaste or having the fluoride enter the digestive system. If any are, the amounts are trace. That makes adults avoiding fluoride because of fears of possible neurodevelopmental and developmental cognitive 'harms' that are linked to long-term overdose of fluoride something that is well beyond reasonable based on scientific evidence.
Natural (not added) fluoride in water is much more likely to be a problem (and that problem is generally minimal) in children. Now, if a child ate about 1/2 a tube of toothpaste that could result in a medical emergency and poison control should be called, but many things we use and eat can cause problems when overdosing.
As for adults, there are known links between poor oral hygiene and cognitive decline and dementia in older adults. Longitudinal studies have shown that toothbrushing (not necessarily specific to use of fluoride, but fluoride is beneficial to dental care, as you stated) is associated with less cognitive decline and lower rates of dementia. Here's a review and meta-analysis: https://doi.org/10.1111/jan.16525
It's fine if you don't want to use toothpaste with fluoride in it, but the risks of any negative cognitive effects from overdosing for years are only clearer in young children. The risks of anything cognitive from fluoride are less clear in adults but as long as you have great dental hygiene, you're okay skipping it. Most people can benefit from what fluoride helps with; namely dental hygiene. Fluoride is one of the things that has a net positive benefit on overall health and functioning when used in typical amounts from water and toothpaste.
Also, if you want to avoid things that have more known negative health and cognitive effects, you should avoid alcohol, pollution, excessive stress, social isolation, and much more.
Neurodetrimental effects: https://ehjournal.biomedcentral.c...hatgpt.com and https://jamanetwork.com/journals/...hatgpt.com. Dental and skeletal fluorosis for folks that apply toothpaste liberally. Most folks don't understand the "pea sized" amounts. https://www.frontiersin.org/journ...hatgpt.com and wikipedia references several more credible sources. Harvard is doing meta analysis on developmental neurotoxicity risks, especially in children. Lot of studies are starting to come out on mouthwash too. Give it 10 years. I take chewable oral prebiotics that include lactobacillus reuteri and my oral hygiene is better than it's ever been. Fluoride is absolutely great for teeth, no questions there. It's everywhere else that concerns me.
The first article shows: "Neurotoxicity appeared to be dose-dependent, and tentative benchmark dose calculations suggest that safe exposures are likely to be below currently accepted or recommended fluoride concentrations in drinking water." It's thus more about drinking water than the small amounts of fluoride in toothpaste. Let's go from there though.
Infants and children (under the age of 6) would likely have to be swallowing a minimum of 5X the normal amount of daily toothpaste for years to have any possible cognitive detriments. Even then, the cognitive harm might be 1-2 IQ points, which difference has no real-world implications. Very few children >6 or adults are swallowing any toothpaste or having the fluoride enter the digestive system. If any are, the amounts are trace. That makes adults avoiding fluoride because of fears of possible neurodevelopmental and developmental cognitive 'harms' that are linked to long-term overdose of fluoride something that is well beyond reasonable based on scientific evidence.
Natural (not added) fluoride in water is much more likely to be a problem (and that problem is generally minimal) in children. Now, if a child ate about 1/2 a tube of toothpaste that could result in a medical emergency and poison control should be called, but many things we use and eat can cause problems when overdosing.
As for adults, there are known links between poor oral hygiene and cognitive decline and dementia in older adults. Longitudinal studies have shown that toothbrushing (not necessarily specific to use of fluoride, but fluoride is beneficial to dental care, as you stated) is associated with less cognitive decline and lower rates of dementia. Here's a review and meta-analysis: https://doi.org/10.1111/jan.16525
It's fine if you don't want to use toothpaste with fluoride in it, but the risks of any negative cognitive effects from overdosing for years are only clearer in young children. The risks of anything cognitive from fluoride are less clear in adults but as long as you have great dental hygiene, you're okay skipping it. Most people can benefit from what fluoride helps with; namely dental hygiene. Fluoride is one of the things that has a net positive benefit on overall health and functioning when used in typical amounts from water and toothpaste.
Also, if you want to avoid things that have more known negative health and cognitive effects, you should avoid alcohol, pollution, excessive stress, social isolation, and much more.
The pros generally don't outweigh the cons and each year the world reduces its use. Not the latter. When it comes to chronic introduction we generally don't understand all the interactions. Circle back in 5 years and we'll see how this ages now that we are better understanding the human microbiome. Ill eat my words if nothing changes.
The pros generally don't outweigh the cons and each year the world reduces its use. Not the latter. When it comes to chronic introduction we generally don't understand all the interactions. Circle back in 5 years and we'll see how this ages now that we are better understanding the human microbiome. Ill eat my words if nothing changes.
If new scientific evidence provides clarity, then I can change my behavior to match. I'm not going to change my behavior on a misunderstanding of the current science or based on speculations of what we might know in the future. You're welcome to do differently, but the known risks of fluoride in toothpaste are minuscule and are much smaller than the benefits.
Think of it like this. It's known that bananas contain isotopes that produce ionizing radiation (potassium-40). Radiation like that can cause cancer. Therefore should we avoid eating bananas? Or avoid if we have a family history of cancer? No. It would take you eating nearly 30,000 bananas in one sitting to get a year's worth of radiation dosage or about 50 million in one sitting to get a lethal dose. If you tried to eat 30,000+ bananas as one meal, you'd have other things to worry about than radiation. Fluoride is easier to overdose on than potassium-40 in bananas but avoiding it as an adult because there might be mild links to mild cognitive changes in childhood is misunderstanding and misapplication of the science. I appreciate your replies, but I don't have time to continue this, and it's getting way off track about this deal.
Neurodetrimental effects: https://ehjournal.biomedcentral.c...hatgpt.com and https://jamanetwork.com/journals/...hatgpt.com. Dental and skeletal fluorosis for folks that apply toothpaste liberally. Most folks don't understand the "pea sized" amounts. https://www.frontiersin.org/journ...hatgpt.com and wikipedia references several more credible sources. Harvard is doing meta analysis on developmental neurotoxicity risks, especially in children. Lot of studies are starting to come out on mouthwash too. Give it 10 years. I take chewable oral prebiotics that include lactobacillus reuteri and my oral hygiene is better than it's ever been. Fluoride is absolutely great for teeth, no questions there. It's everywhere else that concerns me.
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There's considerable evidence of the benefits of fluoride in preventing tooth caries, and not just in children. For example:
Castelo, R., Attik, N., Catirse, A. et al. Is there a preferable management for root caries in middle-aged and older adults? A systematic review. Br Dent J (2021). https://doi.org/10.1038/s41415-021-3003-2
But, if you have peer-reviewed research that shows findings you're concerned about, please provide the references.
Sign up for a Slickdeals account to remove this ad.
Infants and children (under the age of 6) would likely have to be swallowing a minimum of 5X the normal amount of daily toothpaste for years to have any possible cognitive detriments. Even then, the cognitive harm might be 1-2 IQ points, which difference has no real-world implications. Very few children >6 or adults are swallowing any toothpaste or having the fluoride enter the digestive system. If any are, the amounts are trace. That makes adults avoiding fluoride because of fears of possible neurodevelopmental and developmental cognitive 'harms' that are linked to long-term overdose of fluoride something that is well beyond reasonable based on scientific evidence.
Natural (not added) fluoride in water is much more likely to be a problem (and that problem is generally minimal) in children. Now, if a child ate about 1/2 a tube of toothpaste that could result in a medical emergency and poison control should be called, but many things we use and eat can cause problems when overdosing.
As for adults, there are known links between poor oral hygiene and cognitive decline and dementia in older adults. Longitudinal studies have shown that toothbrushing (not necessarily specific to use of fluoride, but fluoride is beneficial to dental care, as you stated) is associated with less cognitive decline and lower rates of dementia. Here's a review and meta-analysis: https://doi.org/10.1111/jan.16525
It's fine if you don't want to use toothpaste with fluoride in it, but the risks of any negative cognitive effects from overdosing for years are only clearer in young children. The risks of anything cognitive from fluoride are less clear in adults but as long as you have great dental hygiene, you're okay skipping it. Most people can benefit from what fluoride helps with; namely dental hygiene. Fluoride is one of the things that has a net positive benefit on overall health and functioning when used in typical amounts from water and toothpaste.
Also, if you want to avoid things that have more known negative health and cognitive effects, you should avoid alcohol, pollution, excessive stress, social isolation, and much more.
Infants and children (under the age of 6) would likely have to be swallowing a minimum of 5X the normal amount of daily toothpaste for years to have any possible cognitive detriments. Even then, the cognitive harm might be 1-2 IQ points, which difference has no real-world implications. Very few children >6 or adults are swallowing any toothpaste or having the fluoride enter the digestive system. If any are, the amounts are trace. That makes adults avoiding fluoride because of fears of possible neurodevelopmental and developmental cognitive 'harms' that are linked to long-term overdose of fluoride something that is well beyond reasonable based on scientific evidence.
Natural (not added) fluoride in water is much more likely to be a problem (and that problem is generally minimal) in children. Now, if a child ate about 1/2 a tube of toothpaste that could result in a medical emergency and poison control should be called, but many things we use and eat can cause problems when overdosing.
As for adults, there are known links between poor oral hygiene and cognitive decline and dementia in older adults. Longitudinal studies have shown that toothbrushing (not necessarily specific to use of fluoride, but fluoride is beneficial to dental care, as you stated) is associated with less cognitive decline and lower rates of dementia. Here's a review and meta-analysis: https://doi.org/10.1111/jan.16525
It's fine if you don't want to use toothpaste with fluoride in it, but the risks of any negative cognitive effects from overdosing for years are only clearer in young children. The risks of anything cognitive from fluoride are less clear in adults but as long as you have great dental hygiene, you're okay skipping it. Most people can benefit from what fluoride helps with; namely dental hygiene. Fluoride is one of the things that has a net positive benefit on overall health and functioning when used in typical amounts from water and toothpaste.
Also, if you want to avoid things that have more known negative health and cognitive effects, you should avoid alcohol, pollution, excessive stress, social isolation, and much more.
The pros generally don't outweigh the cons and each year the world reduces its use. Not the latter. When it comes to chronic introduction we generally don't understand all the interactions. Circle back in 5 years and we'll see how this ages now that we are better understanding the human microbiome. Ill eat my words if nothing changes.
Think of it like this. It's known that bananas contain isotopes that produce ionizing radiation (potassium-40). Radiation like that can cause cancer. Therefore should we avoid eating bananas? Or avoid if we have a family history of cancer? No. It would take you eating nearly 30,000 bananas in one sitting to get a year's worth of radiation dosage or about 50 million in one sitting to get a lethal dose. If you tried to eat 30,000+ bananas as one meal, you'd have other things to worry about than radiation. Fluoride is easier to overdose on than potassium-40 in bananas but avoiding it as an adult because there might be mild links to mild cognitive changes in childhood is misunderstanding and misapplication of the science. I appreciate your replies, but I don't have time to continue this, and it's getting way off track about this deal.
Which probiotics do you take?
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