frontpageRokket | Staff posted Aug 15, 2025 12:56 AM
Item 1 of 4
Item 1 of 4
frontpageRokket | Staff posted Aug 15, 2025 12:56 AM
90-Count Nature Made 250mg Magnesium Oxide Supplement Softgels
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https://pubmed.ncbi.nlm
"Results: For the patient group as a whole, 26Mg absorption was low but was not different for the two supplements (23.5% vs 22.8% for magnesium chelate and MgO, respectively). However, 26Mg absorption was substantially greater from the chelate (23.5% vs 11.8%; p < .05) in the four patients who showed the greatest impairment of magnesium absorption with MgO and was better tolerated by all patients."
Don't get me wrong, it's not useless. But your money is better spent on the glycinate.
That said, NatureMade is a reputable company and they make/sell the glycinate. See here: https://www.amazon.com/Nature-Mad...B0D9MV3YJ
The study described in the linked article was in patients following ileal resection (removal of the last section of the small intestine). The final sentence in the abstract is "Magnesium diglycinate may be a good alternative to commonly used magnesium supplements in patients with intestinal resection." The study was also published in 1994, so it's a little out of date.
A more recent review, Bioavailability of magnesium food supplements: A systematic review, https://pubmed.ncbi.nlm
Conclusions from the full paper included: "There is a difference in bioavailability among different Mg presentation forms, with effervescent tablets or granule formulations better than tablets due to their solubility. The percentage of Mg absorption decreases with increasing dose. Organic forms are better absorbed than inorganic forms."
However, "better absorbed" does not mean other versions are "poorly absorbed" (see my italics above). Cheap MagOxide may still be your best per dollar option.
Magnesium oxide is known for its lower cost and higher elemental magnesium content, but it's poorly absorbed by the body and can cause digestive issues like diarrhea. Magnesium glycinate, on the other hand, is a chelated form that's highly bioavailable (easily absorbed) and generally well-tolerated, with potential benefits for sleep and anxiety reduction.
If you go to the ICU today, in America, where they don't give a crap about the final cost of medicine and you are low are Magnesium you will get MagOx from your hospital doctor.
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https://blog.algaecal.c
"It's true that magnesium oxide is not as easy to render soluble as some other magnesium salts. It's therefore not absorbed as rapidly as other forms of magnesium, e.g. magnesium citrate, gluconate, lactate, aspartate.
But although magnesium oxide has a lower rate of absorption it contains a MUCH greater amount of actual magnesium to begin with. More than what is provided by other magnesium salts.
Therefore, even with the lower rate of absorption, magnesium oxide still delivers more magnesium per tablet. So more magnesium gets into your bloodstream to deliver all its many benefits to your bones and body"
https://blog.algaecal.com/magnesi...wer-pills/ [algaecal.com]
"It's true that magnesium oxide is not as easy to render soluble as some other magnesium salts. It's therefore not absorbed as rapidly as other forms of magnesium, e.g. magnesium citrate, gluconate, lactate, aspartate.
But although magnesium oxide has a lower rate of absorption it contains a MUCH greater amount of actual magnesium to begin with. More than what is provided by other magnesium salts.
Therefore, even with the lower rate of absorption, magnesium oxide still delivers more magnesium per tablet. So more magnesium gets into your bloodstream to deliver all its many benefits to your bones and body"
Also, who calls it a "hospitalist"?
A more recent review, Bioavailability of magnesium food supplements: A systematic review, https://pubmed.ncbi.nlm
Conclusions: All magnesium dietary supplements can maintain physiological levels in healthy people without prior deficit (my italics), although this cannot be assured in older people or those with illnesses or previous subphysiological levels.
However, "better absorbed" does not mean other versions are "poorly absorbed" (see my italics above). Cheap MagOxide may still be your best per dollar option.
This is in stark contrast with Glucosamine HCl, which is completely useless.
Just do a search on "Magtein" and look particularly for Mag w/L-Threonate
Shucks, just ....https://www.amazon.com/dp/B0FBJ49...asin_
- Absorption: Only about 4% bioavailability (poorly absorbed compared to magnesium citrate, glycinate, malate, etc.).
- Usefulness: Because it mostly stays in the gut, it acts more as a laxative than as a good systemic magnesium source.
- Cheap & common: It's inexpensive, which is why it shows up in many multivitamins, but it's not the best choice if you actually want to raise magnesium levels in your blood or tissues.
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